GENERIC NAME:

Dopamine HCl (Hydrochloride)

FORM:

Solution for Injection (IV Infusion)

FORMULATION:

Each mL contains Dopamine (as Hydrochloride) – 40mg

INDICATION AND USAGE:

Dopamine is a symphathomimetic with both direct and indirect effects. It is formed in the body by the decarboxylation of levodopa, and is both a nuerotransmitter in its own right (notably in the brain) and a precursor of nonadrenaline. Dopamine is a sympathomimetic used in acute heart failure, as occurs in cardiogenic shock and myocardial infarction. It is also used in renal failure, in cardiac  surgery and septic shock.

DOSAGE and ADMINISTRATION:

Dopamine is given as the hydrochloride by intravenous infusion as dilute solution (usually 1.6 or 3.2 mg/mL although more dilute solutions may be used where fluid expansion is not a problem), in glucoce 5%, sodium chloride 0.9%, or other suitable diluents. The initial rate is 1 to 5 micrograms/kg per minute, gradually increased by up to 5 to 10 micrograms/Kg per minute according to the patient’s blood pressure, cardiac output, and urine output. Up to 20 to 50 micrograms/kg per minute maybe seriously ill patient; higher dose have been given.

AVAILABILITY:

5mL in USP Type 1 Amber Glass Ampoule blister tray x 5’s (Box of 10’s)